Let’s get Scientific! Aloe Vera may help the body absorb other co-administered compounds!

Composition and Applications of Aloe vera Leaf Gel ………………. Josias H. Hamman writing in The National Center for Biotechnology Information Journal

Extract

Many of the health benefits associated with Aloe vera have been attributed to the polysaccharides contained in the gel of the leaves. These biological activities include promotion of wound healing, antifungal activity, hypoglycemic or antidiabetic effects, anti-inflammatory, anticancer, immunomodulatory and gastroprotective properties.

While the known biological activities of A. vera will be briefly discussed, it is the aim of this review to further highlight recently discovered effects and applications of the leaf gel. These effects include the potential of whole leaf or inner fillet gel liquid preparations of A. vera to enhance the intestinal absorption and bioavailability of co-administered compounds as well as enhancement of skin permeation.

Keywords:

Aloe vera, biological activities, absorption enhancement, skin permeation, excipient

Polysaccharides are found in abundance in Nature and are readily available from sources such as algae (e.g. alginates), plants (e.g. pectin, guar gum, mannan), microbes (e.g. dextran, xanthan gum) and animals (e.g. chitosan, chondroitin) and they can also be produced by means of recombinant DNA techniques. Monosaccharide polymers have many favourable properties such as high stability, non-toxicity, hydrophilicity, biodegradability, gel forming properties and ease of chemical modification. An enormous variety in plant polysaccharide structural composition exists, which is not only associated with different plants, but also with the part of the plant that they originate from, such as the leaves, seeds, roots and tubers.

Many of the health benefits associated with Aloe vera have been attributed to the polysaccharides contained in the gel of the leaves. These biological activities include promotion of wound healing, antifungal activity, hypoglycemic or antidiabetic effects, anti-inflammatory, anticancer, immunomodulatory and gastroprotective properties.

While the known biological activities of A. vera will be briefly discussed, it is the aim of this review to further highlight recently discovered effects and applications of the leaf gel. These effects include the potential of whole leaf or inner fillet gel liquid preparations of A. vera to enhance the intestinal absorption and bioavailability of co-administered compounds as well as enhancement of skin permeation.

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